Cardiovascular Sciences (Research)

Our PhD/MPhil Cardiovascular Sciences programme enables you to undertake a research project that will improve understanding of Cardiovascular Sciences.

Cardiovascular diseases are major causes of mortality and morbidity in developed and developing countries worldwide.

Our research spans five main themes:

• cardiovascular genetics and development;

• experimental cardiology;

• vascular biology/hypertension;

• stroke;

• clinical cardiovascular research;

We adopt an integrated 'bench-to-bedside' translational approach for understanding the underlying mechanisms responsible for the functioning of the cardiovascular system in both health and disease.

To this end, there is a wide spectrum of research spanning clinical trials, small and large animal models of cardiovascular diseases, whole organs and tissues, cells and single molecule studies. Working together in purpose-built facilities provides for a stimulating and cutting-edge environment.

Examples of research programmes include:

• cardiac and vascular electrophysiology;

• cardiac conduction system;

• calcium and second messenger signalling in the heart and vasculature;

• heart failure and arrhythmias;

• hypertrophic signalling pathways in the heart;

• cardiovascular genetics and development;

• cellular and protein structure;

• comparative biology and mitochondrial function;

• computer modelling;

• hypertension, obesity, metabolic syndrome and diabetes research;

• vascular biology of small and large arteries;

• angiogenesis and endothelial biology;

• stroke;

• cardiovascular imaging;

• induced Pluripotent Stem Cell (iPSC) models of cardiovascular disease;

• cardiac and vascular regeneration;

• renal physiology and genetics;

• renal medicine;