Genetics (Research)

The Institute of Genetic Medicine brings together a strong team with an interest in clinical and developmental genetics. Our research focuses on the causes of genetic disease at the molecular and cellular level and its treatment. Research areas include: genetic medicine, developmental genetics, neuromuscular and neurological genetics, mitochondrial genetics and cardiovascular genetics.

As a research postgraduate in the Institute of Genetic Medicine you will be a member of our thriving research community. The Institute is located in Newcastle’s Life Science Centre. You will work alongside a number of research, clinical and educational organisations, including the Northern Genetics Service.

Find out more about the Institute of Genetic Medicine's research areas. We offer supervision for MPhil, PhD and MD in the following research areas:

Cancer genetics and genome instability
Cardiovascular genetics and development
Complex disease and quantitative genetics
Developmental genetics
Gene expression and regulation in normal development and disease
Genetics of neurological disorders
Kidney genetics and development
Mitochondrial disease
Neuromuscular genetics
Stem cell biology
Pharmacy.

Our new School of Pharmacy has scientists and clinicians working together on all aspects of pharmaceutical sciences and clinical pharmacy.

We will be offering the following PhD projects:
•Drug Delivery Approaches for Improved Treatment of Disease
•Targeting Biosynthetic and Regulatory Pathways of Mycobacterium Tuberculosis as Novel Drug Targets
•Design, Synthesis and Target Identification of Novel Anti-Tubercular Agents
•Activity-Based Chemical Probes for the Profiling of Cytochrome P450s
•Development of Novel Silanediol HDAC Inhibitors for the Treatment of Cancer.

Facilities:

We have specialist facilities on-site for:
•multicolour fluorescence-activated cell sorting
•‘next generation’ high-throughput sequencing and genotyping
•transgenics/gene targeting
•confocal microscopy
•optical projection tomography
•gene expression imaging
•microarray technology
•bioinformatics
•fluorescent activated cell sorting
•‘Good Manufacturing Practice’ for human stem cells .